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Probiotic innovated and tested against placebo by NIH research.(1,2)
(1) Myles, Ian A et al. Sci Transl Med 2020 Sep 9;12(560):eaaz8631. doi: 10.1126/scitranslmed.aaz8631.
(2) Myles, Ian A, et al. JCI Insight. 2018 May 3;3(9):e120608. doi: 10.1172/jci.insight.120608.
(1) Myles, Ian A et al. Sci Transl Med 2020 Sep 9;12(560):eaaz8631. doi: 10.1126/scitranslmed.aaz8631.
(2) Myles, Ian A, et al. JCI Insight. 2018 May 3;3(9):e120608. doi: 10.1172/jci.insight.120608.
(1) Myles, Ian A et al. Sci Transl Med 2020 Sep 9;12(560):eaaz8631. doi: 10.1126/scitranslmed.aaz8631.
(2) Myles, Ian A, et al. JCI Insight. 2018 May 3;3(9):e120608. doi: 10.1172/jci.insight.120608.
Defensin™ contains a topical probiotic discovered and tested by a team of doctors to soothe itchy, rashy skin. Probiotics are live microorganisms that provide a health benefit when administered in specific amounts.
Our probiotic strain Roseomonas RSM2015 has been shown to be a ceramide producer. Ceramides are important for retaining your skin's moisture and strengthening skin barrier function. Our live probiotic has been proven safe and effective in placebo controlled clinical trials. Academic research has demonstrated that Roseomonas mucosa RSM2015 is the top probiotic strain for protecting and enhancing the skin barrier. In addition, ground cardamom seed soothes itchy skin caused by the overactivation of TRPA1.
Probiotics are live microorganisms that provide health benefits when administered in adequate amounts. By definition, probiotics must have a scientifically demonstrated health effect. In the case of Defensin™ skin probiotic, our ingredients can be matched to two randomized controlled clinical trials that show safety and efficacy in promoting clear, healthy skin. Our probiotics are one-of-a-kind, patented probiotic strains that are not available generically. Only 1-in-500 probiotic skincare products have a proven health benefit. In addition, many are not live probiotics at all, rather they are lysates, or probiotic byproducts.
Simply send a photo of your opened package for a full refund, no questions asked.
We recommended spraying the probiotic ingredients onto the desired areas where you would like healthier skin. For optimal and sustained results, we suggest continuous, every other day use for at least 90 days.
Clinical evidence shows that Roseomonas mucosa RSM2015 promotes healthier skin.
You may see results within a few days, but clinical evidence from clinics shows that you will get the best benefits for your skin following 90 days of every other day of use.
We encapsulate probiotics proven safe and effective for promoting skin health in double-blind, placebo-controlled controlled clinical trials.
About the Clinical Trials
University-based, double-blind, placebo-controlled trial measured the effects of our probiotic mixtures in skin health
Peer Reviewed & Published
After passing a rigorous review, our gold standard clinical study was published in JAMA Dermatology — a top-tier, internationally recognized, peer-reviewed American medical journal.
A second study was published in ACTA Dermatology - a prominent European medical journal:
Why It Matters
We are incredibly proud of the evidence-based products we formulate, and we believe clinical studies are the best way to directly measure their impact.