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Transform Your Skin Health in Days with Long Lasting Results

Your problematic skin may be caused by a bacteria imbalance. Innovated through research by The National Institutes of Health, here is the breakthrough probiotic solution to enhance and protect your skin barrier for long lasting, healthier skin.

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90-Day Healthy Skin Guarantee

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“THE ORIGINAL PROBIOTIC FOR SKIN®”

Instant Relief with Long-Term Benefits

A skin health breakthrough from over 7 years of research, Defensin™ was designed by a team of doctors at the National Institutes of Health (NIH)


  • Probiotic strain Roseomonas mucosa RSM2015 clinically shown to improve skin health
  • 9 out of 10 of patients achieved clear, healthy skin in the clinical trial.(1)
  • Documented results continued eight months after initial protocol.
  • Innovated and studied by doctors

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We offer an extended 90-Day Money-Back Guarantee. Simply send a photo of your opened package for a full refund.

(1) Myles, an A et al. Sci Trans Med 2020 Sep;12(360)ort611. doi: 10.1126/scism.631.

(2) Myles, Jan A, et al. JCI Insight 2018 May 3,3120608. doi: 10.1172/jinsight 120608.

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Proven Safe & Effective

Probiotic innovated and tested against placebo by NIH research.(1,2)

Start Now (1) Myles, an A et al. Sci Trans Med 2020 Sep;12(360)ort611. doi: 10.1126/scism.631. (2) Myles, Jan A, et al. JCI Insight 2018 May 3,3120608. doi: 10.1172/jinsight 120608.
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Patients saw reduction of itchy, dry, inflamed skin.

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Patients achieved clear, healthy skin.

Start Now (1) Myles, an A et al. Sci Trans Med 2020 Sep;12(360)ort611. doi: 10.1126/scism.631. (2) Myles, Jan A, et al. JCI Insight 2018 May 3,3120608. doi: 10.1172/jinsight 120608.

Incredible Medical Breakthrough

9 out of 10 participants achieved clearer, healthier skin in randomized controlled trials

Why Defensin?

Defensin™ ingredients were tested by doctors in 2 rigorous, double-blind, placebo-controlled clinical studies in dermatology clinics.

HEALTHIER SKIN!

100% natural ingredients clinically proven to improve skin health.(1,2)

CLEAR SKIN!

9 out of 10 participants achieved clearer, healthier skin in the clinical trials.(1,2)

ENHANCED SKIN BARRIER!

Innovated by a team of doctors to enhance and protect your skin.

Note: All testing done by a 3rd party. Our ingredients have been tested against placebo in randomized-controlled clinical trials and published in world class, peer-reviewed medical journals.

(1) Myles, Ion A et al. Sci Transl Med 2020 Sep 9:125608631. doi: 10.1126/scitronsmed.631.
(2) Myles, Ion A, et al JCI Insight, 2018 May 339120608, do 10.1172/jcinsight 120608

PROVEN INGREDIENTS

KEY BENEFITS

Skinesa
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INGREDIENTS

Roseomonas mucosa RSM2015, ground cardamom seeds, sucrose.

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HOW DOES IT WORK

HOW DOES IT WORK

DefensinTM in Action

HOW DOES IT WORK

By introducing good bacteria to the skin, Defensin combats harmful bacteria and rebalances the skin's microbiome. It strengthens the skin barrier, making it resistant to allergens and toxins, while naturally producing ceramides to boost moisture. The results? Healthier, clearer skin.

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PROVEN INGREDIENTS

KEY BENEFITS

Skinesa
Image

INGREDIENTS

Roseomonas mucosa RSM2015,
ground cardamom seeds, sucrose.

Ground cardamom seeds: Specifically selected by experts for their soothing properties, providing immediate relief to itchy skin.
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BEWARE: OTHER TOPICAL
"PROBIOTICS" ARE NOT ACTUALLY PROBIOTCS!

In fact, 99.9% of the topical probiotic lotions on the market do not contain actual live probiotics! Instead, they contain DEAD bacteria byproducts that are referred to as "probiotic lysates."

However: Scientists define probiotics as live
microorganisms that provide a health benefit when applied in specific amounts. The gold standard for verifying a health benefit is the randomized controlled trial (RCT).

Our Solution: A topical probiotic that has demonstrated a positive skin health effect in 3 separate randomized controlled trials.

To achieve your desired skin health outcomes, it's vital your topical probiotic contains an actual live probiotic that has demonstrated the required results with clinical efficacy.

What does this mean for your skin?

Tested by three double-blind, placebo-controlled clinical studies and validated by publication into an American Dermatology journal, the probiotic ingredient in Defensin has helped people just like you....

Achieve Clear, Smooth, Healthy skin!

Get Smooth, Clear,
Healthy Skin!

You can finally promote healthy skin from the inside with a proven method.

90 Day Money Back Guarantee

We know you'll love your skin.We offer an extended 90-Day Money-Back Guarantee. If you're not completely satisfied, we'll refund your money.

90 day guarantee money back 90-Day Healthy Skin Guarantee